Heart Failure Treatment Pattern Analysis of HF Patients in HF Centers and Non-HF Centers in China: a Retrospective Database-based Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22,500
- 试验地点
- 1
- 主要终点
- Number of GDMT drugs (classified as RAASi (including ARNI), beta blockers, MRA and SGLT2i)
研究概览
简要总结
This is a retrospective, researcher-initiated, database-based study that will retrospectively observe the treatment and medication patterns of about 22,500 patients with heart failure from 25 heart failure centers and 25 non-heart failure centers in the database of heart failure center. The proportion of patients with heart failure treatment drugs reaching the target dose recommended in the guidelines and discontinuation rate will be observed at 1 month, 3 months and 12 months follow up time point. The purpose of this study is to illustrate the current HF treatment status in HF center hospitals and non-HF center hospitals, which may provide insights for improving the clinical practice of heart failure treatment in China, and promote the standardization of heart failure treatment in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •An index HF diagnosis date in the records
- •Age ≥ 18 years old at initial diagnosis date
- •HF patients baseline characteristic record
排除标准
- 未提供
结局指标
主要结局
Number of GDMT drugs (classified as RAASi (including ARNI), beta blockers, MRA and SGLT2i)
时间窗: At baseline and at 1 month, 3 month, 12 month follow-up time point
Numbers of GDMT drugs of HF patients stratified by HF ejection fraction and by HF Center and Non-HF Center
Use rates of GDMT drugs
时间窗: At baseline and at 1 month, 3 month, 12 month follow-up time point
The percentage of patients using each GDMT drug，stratified by HF ejection fraction and by HF Center and Non-HF Center
次要结局
- Discontinuation rate of each GDMT drug(at 1 month, 3 month, 12 month follow-up time point)
- The proportion of patients using 2 types of GDMT drugs(At baseline and at 1 month, 3 month, 12 month follow-up time point)
- The proportion of patients using 3 types of GDMT drugs(At baseline and at 1 month, 3 month, 12 month follow-up time point)
- The proportion of patients using 4 types of GDMT drugs(At baseline and at 1 month, 3 month, 12 month follow-up time point)
- The proportion of patients with each GDMT drug in the target dose(at 1 month, 3 month, 12 month follow-up time point)
研究者
Yong Huo
Prof
Peking University First Hospital