The Effects of Including Almonds in an Energy-restricted Diet on Weight, Abdominal Fat Loss, Blood Pressure, and Cognitive Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Post-lunch cognitive function
研究概览
简要总结
The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and ameliorate the post-lunch dip in cognitive function.
详细描述
The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and ameliorate the post-lunch dip in cognitive function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult participants
- •Overweight or obese (BMI 25-40 kg/m2)
- •Fasting blood glucose ≤6.9 mmol/L via capillary finger-stick blood samples
- •No nut allergies
- •Willing to comply to study protocol and to eat test meals
排除标准
- •Those not meeting inclusion criteria.
研究组 & 干预措施
Energy restriction
Energy restriction (-500 kcal/day) (N=40), where participants will receive dietary counseling to reduce energy intake to achieve 500 kcal/day deficits to support weight loss. Participants will also be asked to avoid all nuts during the intervention period.
干预措施: Energy restriction (Behavioral)
Energy restriction with almonds
Energy restriction (-500 kcal/day) with dry-roasted, lightly salted almonds supplying 15% of estimated energy requirement. Participants will receive dietary counseling to reduce energy intake to achieve 500 kcal/day deficits. Energy from almonds will be accounted for during dietary modeling so that a 500 kcal/day deficit is achieved.
干预措施: Almonds (15% kcal/day) (Behavioral)
Energy restriction with almonds
Energy restriction (-500 kcal/day) with dry-roasted, lightly salted almonds supplying 15% of estimated energy requirement. Participants will receive dietary counseling to reduce energy intake to achieve 500 kcal/day deficits. Energy from almonds will be accounted for during dietary modeling so that a 500 kcal/day deficit is achieved.
干预措施: Energy restriction (Behavioral)
结局指标
主要结局
Post-lunch cognitive function
时间窗: 12 weeks
Cognitive function assessments will be performed after a standard lunch at baseline and week 12
Anthropometric measurements
时间窗: 12 weeks
Changes in body weight, BMI, fat mass, waist circumference and abdominal height over 12 weeks
Blood pressure
时间窗: 12 weeks
Blood pressure measurements assessed at baseline, week-4, week-8 and week-12
次要结局
- Physical activity(12 weeks)
- Fasting blood biochemistries(12 weeks)
- Appetite ratings(12 weeks)
- Dietary intake(10 weeks)
研究者
Richard Mattes
Distinguished Professor Nutrition Science
Purdue University