MedPath

JOB STRESS in OPHthalmology Physicians and Residents

Not Applicable
Recruiting
Conditions
Heart Rate Variability
Stress
Interventions
Behavioral: Impact of prolonged work
Registration Number
NCT04959838
Lead Sponsor
University Hospital, Clermont-Ferrand
Brief Summary

Ophthalmology physicians and residents work under stress conditions during night emergency ophthalmology shifts. Under time pressure, that is a characteristic of the urgency of care, they must use all their cognitive resources to make an accurate diagnosis and to provide accurate decisions, with sometimes surgical emergency acts. In addition, in France, they work at night following by an usual day work, and they can also work 48 consecutive hours during weekends, followed by a work day ... i.e. 60 consecutive hours of work ... Long working hours with a short recovery time has been demonstrated to be a major factor of stress and fatigue. Even if not demonstrated on ophthalmologists, those working conditions may contribute to symptoms of mental exhaustion and physical fatigue (sleep deprivation), often accompanied by a loss of motivation at work. This may leads to a feeling of loss of time control; stress can also distort the perception of time and leads to hasty actions or delayed decision-making. The combined effects of stress, feelings of loss of time control, and fatigue necessarily have an impact on work performance and work quality, with a high risk of medical error. Moreover, prolonged stress may expose ophthalmologists to a higher risk of multiple diseases, predominantly systemic inflammation and coronary heart disease.

The main hypothesis is that prolonged work (up to 60 consecutive working hours) may impact on HRV, comparatively to a typical working day.

Detailed Description

The JOBSTRESS.OPH protocol was designed to study the impact of prolonged work (up to 60 consecutive working hours) on HRV, comparatively to a typical working day. Each residents and / or ophthalmology physicians participates up to a maximum of 5 times. Participants wears a heart rate belt and a watch that measures physical activity and skin conductance for 34 hours straight. Participants only wears an EEG monitor while sleeping to assess its quality. At the end of the evaluation session, a simulator test mimicking the successive stages of cataract surgery is performed, as well as the performance of saliva tests. Short quality of life assessment questionnaires are completed at the start and end of the day, supplemented by a general questionnaire completed only once during the study.

Statistical analysis will be performed using Stata software (v15, Stata-Corp, College Station, US). Categorical parameters will be described in terms of numbers and frequencies, whereas continuous variables will be expressed as mean and standard deviation or median and \[inter-quartile range\] according to statistical distribution. All statistical tests will be two-sided and p\<0.05 will be considered significant. Graphic representations will be complete presentations of results.

Investigators process multivariate physiological series (HRV, SC, biomarkers) in order to build a stress index. For such multivariate physiological series, investigators first use change point analysis on each univariate series in order to get clusters with constant parameters, then investigators use classification algorithm on the constant parameters obtained in first step in order to obtain different classes corresponding to different levels of stress. Eventually, investigators obtain at each time the level of stress and can compare it to the environmental conditions.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Ophthalmologists defined as physicians who completed the ophthalmology DES (Specialized studies diploma), as well as ophthalmology residents defined as a resident registered in the ophthalmology DES working during the inclusion period in the ophthalmology department of the university hospital center of Clermont-Ferrand.
  • Ability to give a written informed consent to participate in research.
  • Affiliation to a social security system.
  • Age between 18 and 65 years old
Exclusion Criteria
  • Participant refusal to participate
  • Children under the age of 18, pregnant and breastfeeding women, protected adults (individuals under guardianship by court order), adults deprived of their liberty.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Ophthalmology physicians and residentsImpact of prolonged workOphthalmology physicians and residents will be followed during 34h, from 8 am to 6 pm the following day,in five different conditions: * Control day (no work) * Typical working day * Working day + one night shift * Emergency working day + two consecutive night shifts * Night shift.
Primary Outcome Measures
NameTimeMethod
Heart rate variabilityDuring 34 hours in the five different conditions

HRV will be explored in time and frequency domains Abrupt changes in HRV signals will be explored.

Secondary Outcome Measures
NameTimeMethod
change in anxiety levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of anxiety using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

change in "Effort reward imbalance" levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of effort reward imbalance using visual analogue scale of 100 mm, from 0 to 100. Higher scores of mean a better outcome level.

Saliva biomarkers lgAs24 hours after the beginning of the procedure, in the five different conditions

measure on lgAs

Level of physical activityduring 34 hours, in the five different conditions

Physical activity is assessed with a 3-Axis accelerometer

Saliva biomarkers cortisol24hours after the beginning of the procedure, in the five different conditions

measure on Cortisol

change in sleep qualityat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of sleep quality using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

Saliva biomarkers Leptine24 hours after the beginning of the procedure, in the five different conditions

measure on Leptine

Saliva biomarkers Ghrelin24 hours after the beginning of the procedure, in the five different conditions

measure on Ghrelin

change in work addiction levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of work addiction using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

Food intake34 hours recording, in the five different conditions

assessing food intake with ingesta

change in stress levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of stress using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

change in fatigue levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of fatigue using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

Saliva biomarkers dheas24 hours after the beginning of the procedure, in the five different conditions

measure on dheas

Level of sedentaryonce at 8am, at the beginning of the procedure

Sedentary is assessed regarding the time spent sitting assessed with one question

Ageonce at 8am, at the beginning of the procedure

measure of age in years using a questionnaire

Personal statusonce at 8amat the beginning of the procedure

measure of personal status using a questionnaire

change in depression levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of depression using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

Qualificationonce at 8am, at the beginning of the procedure

measure of qualification using a questionnaire

change in burnout levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of burnout using visual analogue scale of 100 mm, from 0 to 100. Higher scores mean a worse outcome level.

change in "Job demand control support" levelsat 6pm, end of the 34 hours follow-up, in the five different conditions

measure of job demand, job control and support levels using visual analogue scale of 100 mm, from 0 to 100. Higher scores of demand mean a worse level. Higher scores of control and support mean a better level.

Weightonce at 8am, at the beginning of the procedure

measure of weight in kilograms using a questionnaire

Lifestyleonce at 8am, at the beginning of the procedure

Assessing factors related to lifestyle as smoking, alcohol and coffee consumption using a questionnaire

Surgical performanceOnce at 6pm, at the end of the 34 hours follow-up , in the five different conditions

assessing surgical performance using a high-end virtual reality simulator for intraocular surgery training

Declared level of physical activityonce at 8am, at the beginning of the procedure

Physical activity is assessed with one question

Sick leaveonce at 8am, at the beginning of the procedure

assessing the number of absence days the previous 6 months using a questionnaire

Heightonce at 8am, at the beginning of the procedure

measure of height in cm using a questionnaire

Genderonce at 8am, at the beginning of the procedure

measure of gender using a questionnaire

Skin conductanceduring 34 hours , in the five different conditions

measure of the skin conductance using Wrist band electrodes

Sleep qualitymeasure for about 7 hours during the night of the typical working day

measure of sleep quality using Sleep profiler

Trial Locations

Locations (1)

CHU clermont-ferrand

🇫🇷

Clermont-Ferrand, France

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