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Clinical Trials/NCT02166411
NCT02166411
Completed
Phase 2

Laparoscopic Myomectomy Using Barbed or Conventional Sutures . A Randomized Controlled Trial

Cairo University1 site in 1 country92 target enrollmentJanuary 2014
ConditionsFibroid

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Fibroid
Sponsor
Cairo University
Enrollment
92
Locations
1
Primary Endpoint
Operative time
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study is to compare operative data and early postoperative outcomes of laparoscopic myomectomy using barbed sutures with those of laparoscopic myomectomy using conventional sutures .

Detailed Description

• Till now , there is only one small randomized controllrd study (n=22 in each arm) which compared the use of barbed suture with conventional suture in laparoscopic myomectomy .The myoma bed was closed with either conventional polyglactin suture or unidirectional barbed suture . The operative time was shorter in the barbed suture group (73.3 ± 21.4 min Vs. 80.7 ± 18.6 min) but this difference failed to reach statistical significance because of small sample size . However, the time required to suture the myoma beds was significantly lower in the barbed suture group .

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
January 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Usama M Fouda

M.D, PhD

Cairo University

Eligibility Criteria

Inclusion Criteria

  • the presence of one to three symptomatic intramural or subserosal myomas (with largest fibroid diameter less than 10 cm).

Exclusion Criteria

  • submucosal myoma
  • calcified myomas
  • uterine size more than 16 weeks
  • suspension of genital malignancy
  • coagulation defects or concurrent anticoagulant therapy
  • pregnancy
  • compromised cardiopulmonary status
  • previous treatment with gonadotropin-releasing hormone analogue
  • contraindications for general anesthesia.

Outcomes

Primary Outcomes

Operative time

Time Frame: During myomectomy operation

Secondary Outcomes

  • Suturing time of myoma bed(During myomectomy operation)

Study Sites (1)

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