Exercise Training in Patients With Pulmonary Arterial Hypertension
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Other: Kettlebell Exercise
- Registration Number
- NCT05242380
- Lead Sponsor
- Saglik Bilimleri Universitesi
- Brief Summary
In this study, the effects of kettlebell exercise training on functional capacity, dyspnea and activities of daily living in patients diagnosed with Pulmonary Arterial Hypertension (PAH) will be investigated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
- Patients diagnosed with pulmonary arterial hypertension (PAH) by a specialist physician in accordance with the 2015 guideline for the treatment and diagnosis of pulmonary hypertension of the European Heart and Respiratory Societies (ERS/ESC),
- Patients with stable pharmacological treatment,
- Patients clinically stable at least last three months.
- Presence of orthopedic or neurological problems that will affect functional tests and muscle strength measurement,
- Recent surgical procedures,
- Recent syncope,
- Pregnancy,
- Presence of severe left heart failure,
- Presence of severe ischemic heart disease,
- Hypertensive patients,
- Patients who have problems in communicating.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Kettlebell Exercise Kettlebell Exercise 8-week, 3-day/week supervised training will be applied to the participants in this group. After the initial assessment, patients in this group will receive a one-session education on the pathophysiology of PAH, the benefits of physical activity, and energy conservation techniques during activities of daily living. Pharmacological treatment of patients in this group will be continued.
- Primary Outcome Measures
Name Time Method Task related oxygen uptake 8 weeks Cardiopulmonary data will be evaluated with mobile cardiopulmonary exercise test during daily activities. Participants will perform the following activities with mobile cardiopulmonary exercise test (CPET): putting on socks on both feet (sitting on a chair), putting on both shoes (sitting on a chair), putting on a coat (while standing), lifting material (placing 6 jars -each 400 gram- at chest-level height), sweeping the floor for 4 minutes, washing dishes for 4 minutes, go up and down stairs - 1 floor. There will be a 5 minute rest between all activities.
Peripheral muscle strength 8 weeks Isometric muscle strength will be measured with a handheld dynamometer for elbow flexion, knee extension, knee flexion, shoulder flexion, shoulder abduction, hip flexion and m.serratus anterior.
Handgrip strength 8 weeks Hand grip strength will be measured with a digital hand dynamometer.
Functional capacity 8 weeks The 6-minute walk test will be performed.
- Secondary Outcome Measures
Name Time Method Activity status 8 weeks This outcome will be assessed with the Duke Activity Status Index. As a result of scoring, a total score ranging from 0 to 58.2 is obtained. Higher scores indicate higher functional capacity.
Health-related quality of life 8 weeks This outcome will be assessed with the emPHasis-10. emPHasis-10 consists of 10 items and results in a score out of 50, where a higher score represents a higher symptom burden.
Activities of daily living 8 weeks This outcome will be assessed with the London Chest Activity of Daily Living Scale. It is a questionnaire consisting of fifteen items. Each item is given a score ranging from 0 to 5. Higher scores indicate greater limitation in activities of daily living. The total score can reach a maximum of 75
Sleep quality 8 weeks This outcome will be assessed with the Pittsburgh Sleep Quality Index. The questionnaire consists of 19 individual items. Each item is given a score ranging from 0 to 3, providing an overall score ranging from 0 to 21, where lower scores denote a healthier sleep quality.
Trial Locations
- Locations (1)
Istanbul University - Cerrahpasa, Institute of Cardiology
🇹🇷Istanbul, Turkey