A study comparing two groups of drug combination for better outcome for intubation in cancer patients.

Not Applicable

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2023/07/054860
• Lead Sponsor: Department of Onco- Anaesthesia and Palliative Medicine AIIMS New Delhi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients with head and neck cancers and anticipated difficult intubation.

2. Patients aged between 18 - 65 years of both genders

3. Patients who upon being explained the procedure are willing to participate in the study, and gave informed consent

Exclusion Criteria

1. Patients who are uncooperative to awake fiberoptic intubation.

2. Patients allergic to drugs/ medication being used in the procedure that is dexmedetomidine, midazolam, ketamine, and propofol.

3. Patients having major cardiac, neurological, hepatic, renal, pulmonary illness or coagulation abnormalities.

4. Patients with uncontrolled diabetes mellitus, hypertension or heart block.

5. Patients who are on beta-blockers.

6. Patients with a history of bleeding diathesis.

7. Patients with bradyarrhythmia.

8. Asthmatic patients.

9. Pregnant women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evel of sedation: This will be evaluated by Ramsay sedation scoreTimepoint: 0 MINS, 2 MINS, 3 MINS, 5 MINS

Secondary Outcome Measures

Name	Time	Method
1.Intubation Scores: After insertion of fiberoptic scope to visualization of vocal cords <br/ ><br>2.Intubation time: Time from insertion of fiberoptic scope to confirm placement of endotracheal tube. <br/ ><br>3.Patient comfort score <br/ ><br>4.Patient satisfaction- postoperative period <br/ ><br>5.Hemodynamic parameters- Heart rate; Systolic Blood Pressure and Diastolic Blood Pressure; Mean Arterial Pressure; Spo2: Baseline 0 minutes, 2 minutes, 3, 4, 5, 6 minutes <br/ ><br>6.Side effects- Intra and postoperative complications within 24 hours <br/ ><br>Timepoint: Immediate