A Study to compare the effects of different combination of sedative drugs in patients undergoing surgery for head and neck cancer
Phase 4
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynxHealth Condition 2: O- Medical and SurgicalHealth Condition 3: O- Medical and Surgical
- Registration Number
- CTRI/2024/06/069417
- Lead Sponsor
- Department of Anesthesiology Sawai Mansingh Medical College Jaipur Rajasthan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient undergoing head and neck cancer surgeries requiring awake nasotracheal intubation with flexible bronchoscope, patient willing to participate in the study, adult patient aged between 30-70 years of either gender, patient belonging to ASA grade I,II,III.
Exclusion Criteria
Patients with history of obstructive sleep apnoea, nasal trauma, nasal surgery and bleeding diathesis, patient with history of allergy to the study drugs, non-cooperative or mentally retarded patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1-Mean time required for intubation in minutes <br/ ><br>2-Sedation score-Observers Assessment of Alertness score/Sedation Score (OAA/S) <br/ ><br>3-ease of intubation scoreTimepoint: 1-Baseline <br/ ><br>2-10 minutes after the drug infusion <br/ ><br>3-one minute post intubation
- Secondary Outcome Measures
Name Time Method Mean of Haemodynamic parameters (HR,SpO2, SBP, DBP, MAP), proportion of cases with complications, recall of procedureTimepoint: Just after surgery, 1 hour after surgery