Mannose-binding Lectin Deficiency and the Risk of Infectious Complications in Trauma Patients.
- Conditions
- (Multiple) organ failureInfections10019815
- Registration Number
- NL-OMON31242
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Trauma patients admitted to the shock room of the emergency department of the Academic Medical Center, Amsterdam. These patients either meet the criteria of high energy trauma, or are otherwise suspected to have potentially life threatening injuries.
Exclusion Criteria
Patients younger then 18 years old.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Plasma concentration levels of MBL in trauma patients.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Development of infectious complications and death within the first 30 days<br /><br>after trauma in relationship to baseline and follow-up plasma levels of MBL.<br /><br>- ISS, age, gender, region of injury, mortality.<br /><br>- pneumonia, ARDS, SIRS, MOF, sepsis, wound infection, wound dehiscence,<br /><br>urinary tract infection, intra-abdominal abscess.</p><br>