Pulse EnRiched Food and Exercise Clinical Trials (PERFECT Project): Part 1 - Acute Effects of Pulse Ingredients in Snack Products on Appetite, Blood Glucose, and Food Intake in Adults - Study 2
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 主要终点
- Food Intake
研究概览
简要总结
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse products.
We hypothesize that cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake responses compared to non-pulse cereals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
- •BMI of 18.5-29.9 kg/m2
排除标准
- •Restrained eaters
- •Regularly skip breakfast
- •Competitive sports or athletic training at a high intensity
- •Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year.
- •Those unable to walk for an hour continuously
研究组 & 干预措施
Cereal with pea protein
Pea protein
干预措施: Pea protein (Other)
Cereal control
100% Wheat Flour
干预措施: Control (Other)
Cereal with pea starch
Pea starch
干预措施: Pea starch (Other)
Cereal w/ pea starch + pea fibre: 5g
Pea starch + pea fibre: 5g
干预措施: Pea fibre + pea starch (Other)
Cereal w/ pea protein + pea starch: 10g
Pea protein + pea starch: 10g
干预措施: Pea protein + pea starch (Other)
Cereal w/ pea protein + pea fibre + pea starch: 20g
Pea protein + pea fibre + pea starch: 20g
干预措施: Pea fibre + pea starch + pea protein (Other)
结局指标
主要结局
Food Intake
时间窗: at 120 min
Measured by VAS questionnaire
Plasma Glucose and Insulin Concentrations
时间窗: 0 - 200 min
Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits
Subjective Appetite
时间窗: 0-200 min
Motivation-to-eat VAS questionnaire
次要结局
- Physical comfort(0 - 200 min)
- Energy/fatigue(0-200 min)
- Palatability of treaments and meal(5 and 140 minutes)