Pulse EnRiched Food and Exercise Clinical Trials (PERFECT Project): Part 2 - Acute Effects of Pulse Ingredients in Food Products on Aerobic Endurance and Substrate Oxidation During Exercise, as Well as, the Blood Glucose, Insulin, Lactate and Food Intake Response Following an Endurance Exercise Session in Adults - Study 3
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Manitoba
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Plasma Glucose and Insulin Concentrations
Study Overview
Brief Summary
The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. We hypothesize that consumption of bagels containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. We also hypothesize that consumption of bagels containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
- •BMI of 18.5-29.9 kg/m2
Exclusion Criteria
- •Restrained eaters
- •Regularly skip breakfast
- •Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity)
- •Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
- •Those unable to walk for an hour continuously
Arms & Interventions
Bagel with pea flour
Pea flour (30%)
Intervention: Pea flour (Other)
Bagel with pea fibre
Pea fibre (11g)
Intervention: Pea fibre (Other)
Bagel control
100% wheat flour
Intervention: Control (Other)
Bagel w/ pea flour + pea fibre
Pea flour (30%) + pea fibre (11g)
Intervention: Pea flour and pea fibre (Other)
Bagel w/ pea flour + pea protein
Pea flour (30%) + pea protein (24g)
Intervention: Pea flour and pea protein (Other)
Bagel w/ pea flour + pea fibre + pea protein
Pea flour (30%) + pea fibre (11g) + pea protein (24g)
Intervention: Pea flour + pea fibre + pea protein (Other)
Outcomes
Primary Outcomes
Plasma Glucose and Insulin Concentrations
Time Frame: 0-240
Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits
Food Intake
Time Frame: 120 min
Ad-libitum meal
Subjective Appetite
Time Frame: 0-240 min
Motivation-to-eat VAS questionnaire
Exercise intensity
Time Frame: 60-120 min
Oxygen consumption measured during exercise at 3 time points
Secondary Outcomes
- Palatability(5 and 260 min)
- Lactate concentration(60-120 min)
- Substrate Oxidation(60-120 min)
- Energy/fatigue(0 - 240 min)
- Heart rate(60-120 min)
- Physical comfort(0-240 min)