Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/CTRI/2021/08/035855
CTRI/2021/08/035855Not yet recruitingPhase 2/3

COMPARISON OF THE EFFECT OF PRE OPERATIVE NEBULISATION OF DEXMEDETOMIDINE AND CLONIDINE ON POST OPERATIVE SORE THROAT

mithrarajasegar1 site in 1 country64 target enrollmentStarted: August 30, 2021Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Trial Snapshot

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Enrollment
64
Locations
1
Primary Endpoint
INCIDENCE AND SEVERITY OF SORE THROAT
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

post operative sore throat occurs in 25 to 65% of patients undergoing general anesthesia with endotracheal intubation with considerable morbidity and discomfort which causes delay in starting oral feeds.it is second most anesthesia related complication.hence we designed  this study to compare the effects of pre operative nebulisation of two alpha 2 agonists dexmedetomidine and clonidine which can prevent post operative sore throat with minimal side effects

Study Design

Study Type
Interventional
Allocation
Stratified block randomization
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •asa physical status 1 and 2.

Exclusion Criteria

  • •PREVIOUS HISTORY OF SORE THROAT FOR PAST ONE WEEK CHRONIC SMOKER,ASTHMA,CPOD,ORAL INJURIES,HEAD AND NECK INJURIES DIFFICULT AIRWAY (MP 3 OR 4) PREGNANT OR LACTATING WOMEN PATIENT REFUSAL.

Outcomes

Primary Outcomes

INCIDENCE AND SEVERITY OF SORE THROAT

Time Frame: INCIDENCE AND SEVERITY OF SORE THROAT after surgery for three consecutive days.(post operative day 1,2,3)

Secondary Outcomes

  • BLOOD PRESSURE AND HEART RATE(ADVERSE EFFECTS)

Investigators

Sponsor
mithrarajasegar
Sponsor Class
Other [Self ]

Study Sites (1)

Loading locations...

Similar Trials

Not yet recruiting
Not Applicable
Effect of dexamethasone,ketamine,magnesium sulphate nebulization on attenuation of sore throat,hoarseness of voice and cough in general anaesthesia
CTRI/2023/06/053612FORTIS HOSPITAL, MOHALI140
Not yet recruiting
Not Applicable
TO KNOW THE EFFECT OF MAGNESIUM SULPHATE NEBULISATION TO PREVENT POST OPERATIVE SORE THROAT FOLLOWING I-GEL INSERTION FOR GENERAL ANAESTHESIA
CTRI/2022/07/044386DR AMITHKUMAR S K48
Completed
Phase 3
Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore ThroatSore Throat
NCT03729973Zagazig University100
Not yet recruiting
Not Applicable
Usefulness of local anesthetic injection around the nerve, before surgery, on drug requirement to reduce pain in patients undergoing nasal surgeries.
CTRI/2019/11/022114Mahatma Gandhi Medical College and Research Institite50
Completed
Not Applicable
Effect of Intraoperative Neuromuscular Blockade on Postoperative Sore Throat and HoarsenessSore Throat
NCT03397797SMG-SNU Boramae Medical Center117