COMPARISON OF DIFFERENT DOSES OF NALBUPHINE AS AN ADJUVANT IN SPINAL ANESTHESIA IN LOWER ABDOMEN AND LOWER LIMB SURGERIES

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/11/038007
• Lead Sponsor: Dr Tavleen Kaur Brar

Brief Summary

Comparison of two different doses of nalbuphine as an adjuvant to hyperbaric bupivacaine in subarachnoid block for elective lower abdomen and lower limb surgeries and determine the Optimum dose with quicker onset, Duration of sensory and motor block, Duration of analgesic effect, Side effects

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-07-11
• Study Start: 2021-11-22

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age between 18 to 60 years of either gender.
• ASA grade I and II.
• Patients posted for elective lower abdomen and lower limb surgeries under spinal anaesthesia.
• Weight of the patient being in normal range for that age and sex.
• Patients who are not on any antihypertensive, anti-platelet, fibrinolytic or anticoagulant drugs.
• Haemodynamically stable patients with normal laboratory investigations.
• Patients who give informed consent and are willing to be a part of the study.

Exclusion Criteria

• Patients with pre-existing cardiovascular diseases (IHD, hypertension, valvular heart disease), deranged liver functions or renal functions.
• Patients with any neurological or psychiatric disorders.
• Patients posted for emergency procedures 5.
• History of allergy to any of the drugs being used under study 6.
• Unwilling patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determine the	0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins
1-Optimum dose with quicker onset	0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins
2-Duration of sensory and motor block	0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins
3-Duration of analgesic effect	0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins
4-Side effects, if any	0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins

Secondary Outcome Measures

Name	Time	Method
To study the	1-Onset time of sensory block

Trial Locations

Locations (1)

OPD Building, HiTech OT, 5th Floor; 🇮🇳 Pune, MAHARASHTRA, India

OPD Building, HiTech OT, 5th Floor

🇮🇳Pune, MAHARASHTRA, India

Dr Tavleen Kaur Brar

Principal investigator

9592911024

tavleenbrar95@yahoo.in