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Clinical Trials/NCT02482220
NCT02482220
Unknown
Not Applicable

Physical Activity and Energy Intake Control in Obese Adolescents: Effect of Exercise Programs of Various Intensities

Université Blaise Pascal, Clermont-Ferrand1 site in 1 country70 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pediatric Obesity
Sponsor
Université Blaise Pascal, Clermont-Ferrand
Enrollment
70
Locations
1
Primary Endpoint
change in Energy intake in kcal is being assessed
Last Updated
9 years ago

Overview

Brief Summary

Acute exercise of high intensity has been shown to induced nutritional adaptations in obese adolescents. Indeed, several studies have shown that about 30 minutes of intensive exercise (above 70% of the adolescents maximal aerobic capacities) can favor reduced-energy consumption at the following meal with no modification of their appetite feelings. Although it is suggested that chronic physical activity programs can induce energy intake modifications, this has never been clearly studied. The aim of this work is to compare different physical activity programs (low vs. high intensity programs) in terms of energy intake, appetite feelings and appetite-regulating hormones, in obese adolescents.

Detailed Description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations: * anthropometric measurements * Body composition assessed by DXA * Maximal aerobic test * Blood samples (appetite-regulating hormones) * daily energy intake assessment during a 24h intake exploration. The adolescents recruited will then be randomly assigned to one of the two intervention groups: - High Intensity program or moderate intensity program. Those two physical activity programs will last 4-months and will be composed of 3 to 4 exercise sessions per week. The High intensity program will consists in High intensity interval exercises starting at 70% of the adolescents' capacities at the beginning to end around 95%. The moderate intensity program will propose continuous exercises set between 50-65% VO2max. No energy intake intervention will be performed. By the end of the 4-months intervention, all the clinical examinations performed before the intervention will be repeated.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
December 2017
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Université Blaise Pascal, Clermont-Ferrand
Responsible Party
Principal Investigator
Principal Investigator

THIVEL David

PhD, As/Pr, Research scientist

Université Blaise Pascal, Clermont-Ferrand

Eligibility Criteria

Inclusion Criteria

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion Criteria

  • metabolic disorders
  • food disorders
  • physical disability

Outcomes

Primary Outcomes

change in Energy intake in kcal is being assessed

Time Frame: energy intake will be assessed during 24h during the week before the intervention (T0) and the week after (T1)

daily energy intake will be assessed

Study Sites (1)

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