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Clinical Trials/NCT02484612
NCT02484612
Unknown
Not Applicable

Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status

Université Blaise Pascal, Clermont-Ferrand0 sites30 target enrollmentSeptember 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pediatric Obesity
Sponsor
Université Blaise Pascal, Clermont-Ferrand
Enrollment
30
Primary Endpoint
energy intake in kcal
Last Updated
9 years ago

Overview

Brief Summary

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.

Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.

The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Detailed Description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations: * anthropometric measurements * Body composition assessed by dual energy x-ray absorptiometry * Maximal aerobic test They will then randomly complete the following conditions: * CON: a control day without exercise; * HIE: an exercise day with an exercise set at 75% of the capacities * LIE: an exercise day with an exercise set at 40% of the capacities The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted. Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

Registry
clinicaltrials.gov
Start Date
September 2016
End Date
December 2017
Last Updated
9 years ago
Study Type
Interventional
Study Design
Factorial
Sex
Male

Investigators

Sponsor
Université Blaise Pascal, Clermont-Ferrand
Responsible Party
Principal Investigator
Principal Investigator

THIVEL David

PhD, As/Pr, Research scientist

Université Blaise Pascal, Clermont-Ferrand

Eligibility Criteria

Inclusion Criteria

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion Criteria

  • metabolic disorders
  • food disorders
  • physical disability

Outcomes

Primary Outcomes

energy intake in kcal

Time Frame: up to 2 months

buffet meal

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