A study on efficacy and outcome of autologous particulated tooth with platelet rich fibrin as bone graft in extraction socket preservation: A prospective clinical study.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- High Biocompatibility and Patient Safety.
研究概览
简要总结
Autologous tooth as a bone graft material involves the use of a patient extracted tooth free from caries and infections along with PRF processed into a graft material for new bone formation
Dentin has an Osteoconductive Osteoinductive and Osteogenic properties promoting bone regeneration and healing
The structural compositional and histological similarities between dentin and bone both containing hydroxyapatite crystals type I collagen its biocompatibility regenerative potential and growth factors that promote Osteogenesis make it an effective bone graft material
It eliminates the risk of immune rejection and disease transmission associated with Allografts and Xenografts
The process involves crushing the tooth into fine particles to expose the collagen matrix and growth factors by adding Platelet Rich Fibrin enhancing the ability to support bone formation
This graft can be used in extracted socket preservation Implant dentistry alveolar ridge augmentation periodontology maxillofacial surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group from 18 to 50 years
- •Patients requiring extractions.
- •Extracted teeth free from caries, restorations and infections.
- •Tooth with poor prognosis without pulp involvement 5.Periodontally compromised tooth
- •Patients willing to participate in the study.
排除标准
- •Edentulous patients.
- •Endodontically treated tooth.
- •Tooth associated with any benign or malignant pathological conditions like cysts and tumors.
- •Patients with systemic conditions affecting bone metabolism.
- •Patients under medication affecting bone metabolism.
- •Tooth with periapical abscess.
- •Tooth with grossly decayed or root stumps.
结局指标
主要结局
High Biocompatibility and Patient Safety.
时间窗: 6 weeks
Cost-Effectiveness.
时间窗: 6 weeks
Research-Specific Outcomes.
时间窗: 6 weeks
Enhance Bone Regeneration.
时间窗: 6 weeks
Accelerated Healing Process.
时间窗: 6 weeks
次要结局
- New bone formation(6 weeks)