A Dried blood spot sampling method for VANcomycin and Creatinine monitoring: Effectiveness Demonstrated in Outpatient Parenteral Antibiotic Therapy service

• Conditions: concentration of antibiotic in blood following infection; 10004018

• Registration Number: NL-OMON53282
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 88

Inclusion Criteria

- Aged 18 and over
- Able to understand written information and able to give informed consent
- Hospitalized
- Treated with intravenous vancomycin and to be discharged with vancomycin OPAT
service with minimal 1 planned outpatient vancomycin TDM order
- Able and willing to perform finger pricks for dried blood spot sampling, or
able and willing to undergo finger pricks performed by family members or other
caregivers
- Able and willing to fill in questionnaires

Exclusion Criteria

- Former participation in this trial
- Cognitive dysfunction or other dysfunctionalities which makes the patient
unable to draw blood by a fingerprick or fill out questionnaires
- Unable to sample an adequate DBS after training in the hospital (this is also
applicable for family members or other caregivers who are failing to perform
adequate DBS sampling for the patient)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the amount of outpatient visits regarding<br /><br>vancomycin therapy.</p><br>