ACTRN12609000949280招募中不适用
Comparative effects of intraduodenal macronutrients, carbohydrate, lipid and protein, and combinations of lipid and protein, on antropyloroduodenal motility, gut hormones, appetite and energy intake in lean subjects
A/Prof Christine Feinle-Bisset0 个研究点目标入组 20 人开始时间: 2009年11月4日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 55 Years（—）
- 性别
- Male
入选标准
- •Subjects will all be healthy males between age 18 -55 years, with a body mass index (BMI) of 18 - 25 kg/m2. Subjects will be required to be unrestrained eaters, consume less than 20g of alcohol per week, be non-smokers, free of gastrointestinal or chronic disease and not currently taking medication.
排除标准
- •Each subject will be questioned prior to the study to exclude:
- •(1)significant GI symptoms; disease or surgery
- •(2)current use of prescribed or non-prescribed medications (including vitamins and herbal supplements) which may affect energy metabolism, GI function, body weight or appetite (eg domperidone and cisapride, anticholinergic drugs (eg atropine), metoclopramide, erythromycin, hyoscine, orlistat, green tea extracts, Astragalus, St Johns Wort etc.)
- •(3)diabetes mellitus
- •(4)individuals with low blood iron levels
- •(5)epilepsy
- •(6)cardiovascular or respiratory disease
- •(7)any other significant illness as assessed by the investigator
- •(8)allergy to local anaesthetic
- •(9)intake of > 20 g alcohol on a daily basis
- •(10)smokers (cigarettes/cigars/marijuana)
- •(11)unrestrained eaters, as determined by a score of =12 on the eating restraint questionnaire component of the eating questionnaire.
研究者
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