NCT01755663Unknown4 期
Comparison of Efficacy and Safety of Ivabradine Versus Metoprolol for Controlling Heart Rate Prior to 640-Slice Computed Tomographic Angiography in Elective Patients
Col. Suthee Panichkul1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2014年12月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Heart rate of patient before CT coronary
研究概览
简要总结
Ivabradine may be better than Metoprolol for controlling heart rate before Coronary CTA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective patient on scheduled for 640 slices CT coronary at Phramonkutklao hospital
- •Resting heart rate > 70 BPM
- •age > 18 years and informed consent
排除标准
- •Heart rate > 100 BPM
- •BP <100/60 mmHg
- •recent congestive heart failure in 1 mo.
- •SA node, AV node disease and AF
- •on permanent pacemaker
- •CrCL < 15ml/min. , AST or ALT > 3x UNL
- •on HR reducing drug such as diltiazem, verapamil, digitalis
- •contraindication for ivabradine or metoprolol
研究组 & 干预措施
Ivabradine
Experimental
Patients will recieved ivabradine(5) 1 tab bid pc for 3 day and the day of CT, and recieve placebo of metoprolol
干预措施: Ivabradine and Metoprolol (Drug)
metoprolol
Active Comparator
Metoprolol (100) 1/2 tab bid pc for 3 day and the day of CT coronary , and placebo of ivabradine
干预措施: Ivabradine and Metoprolol (Drug)
结局指标
主要结局
Heart rate of patient before CT coronary
时间窗: 1 January 2013 to 31 december 2013
次要结局
- safety and side effect of Metoprolol and Ivabradine(1 january 2013 to 31 december 2013)
研究者
Col. Suthee Panichkul
Col. Suthee Panichkul
Phramongkutklao College of Medicine and Hospital
研究点 (1)
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