Effects of Dietary Protein on Undesirable Postprandial Events in Overweight Subjects
Not Applicable
Completed
- Conditions
- Overweight
- Interventions
- Dietary Supplement: Postprandial metabolic and functional measures
- Registration Number
- NCT00931151
- Brief Summary
Dietary protein differing by their amino acid composition could modulate undesirable metabolic and functional responses to a meal rich in saturated fat and sugars. This study aims at examining the specific effects of dairy protein with different cysteine contents on the postprandial undesirables effects elicited by the ingestion of a high fat meal in overweight subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 10
Inclusion Criteria
- BMI between 25 and 30
- Waist circumference > 94 cm
Exclusion Criteria
- Allergy to milk protein
- Abusive drug consumption
- Smoking
- Hypertension, diabetes
- High level of physical activity
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Casein Postprandial metabolic and functional measures Protein source in the high fat meal is casein Milk soluble protein Postprandial metabolic and functional measures Protein source in the high fat meal are milk soluble protein Alpha lactalbumin Postprandial metabolic and functional measures Protein source in the high fat meal is alpha-lactalbumin
- Primary Outcome Measures
Name Time Method Endothelial dysfunction 0-2-4-6 hours (after meal ingestion)
- Secondary Outcome Measures
Name Time Method Postprandial inflammation 0-0.5-1-1.5-2-3-4-6 hours (after meal ingestion)
Trial Locations
- Locations (1)
Centre de recherche sur volontaires
🇫🇷Bobigny, France