Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects

Not Applicable

Completed

• Conditions: Obesity; Postprandial Lipemia; Atherosclerosis; Inflammation; Postprandial Incretins
• Interventions: Dietary Supplement: Whey Isolate; Dietary Supplement: Caseine; Dietary Supplement: Cod; Dietary Supplement: Gluten

• Registration Number: NCT00863564
• Lead Sponsor: Aarhus University Hospital

Brief Summary

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.

Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-03
• Study First Submitted: 2009-03-17
• Study First Submitted QC: 2009-03-17
• Study First Posted: 2009-03-18
• Primary Completion: 2009-10
• Study Completion: 2009-10
• Status Verified: 2009-11
• Last Update Submitted: 2009-11-09
• Last Update Posted: 2009-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• BMI > 30 kg/m2 & < 45 kg/m2

Exclusion Criteria

• Diabetes
• Lipid lowering drugs
• Liver-, Kidney- and/or Heart Disease
• Serious Hypertension (160/110)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Whey Isolate	Whey Isolate	-
Caseine	Caseine	-
Cod	Cod	-
Gluten	Gluten	-

Primary Outcome Measures

Name	Time	Method
Triglyceride	0h- 2h- 4h- 6h- 8h postprandial

Secondary Outcome Measures

Name	Time	Method
Incretins	0h -1h -2h -4h -6h -8h Postprandial
Inflammatory markers	0h- 1h- 2h- 4h- 6h- 8h postprandial

Trial Locations

Locations (1)

Department of Clinical Nutrion; 🇩🇰 Aarhus, Denmark