Effects of Dietary Proteins on Postprandial Lipaemia and Incretin Responses in Obese Subjects

Not Applicable

Completed

• Conditions: Postprandial Lipaemia; Postprandial Incretins; Postprandial Inflammation
• Interventions: Dietary Supplement: Casein; Dietary Supplement: Whey Isolate; Dietary Supplement: Whey Hydrolysate; Dietary Supplement: Alphalact-Albumin

• Registration Number: NCT00809874
• Lead Sponsor: Aarhus University Hospital

Brief Summary

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.

Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-02
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Study First Submitted: 2008-12-16
• Study First Submitted QC: 2008-12-16
• Study First Posted: 2008-12-17
• Status Verified: 2009-11
• Last Update Submitted: 2009-11-09
• Last Update Posted: 2009-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• BMI >30 kg/m2 & <45 kg/m2

Exclusion Criteria

• Diabetes
• lipid lowering drugs
• Liver-, Kidney- and/or Heart Disease
• Serious Hypertension (160/110)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Casein	Casein	-
Whey Isolate	Whey Isolate	-
Whey Hydrolysate	Whey Hydrolysate	-
Alphalact-Albumin	Alphalact-Albumin	-

Primary Outcome Measures

Name	Time	Method
Triglyceride	0h- 1h- 2h- 4h- 6h- 7h- 8h postprandial

Secondary Outcome Measures

Name	Time	Method
Incretins	0h -1h -2h -4h -6h -7h -8h Postprandial

Trial Locations

Locations (1)

Department of Clinical Nutrion; 🇩🇰 Aarhus, Denmark