Fats And Carbohydrates Quality on Postprandial glycemIc Response in Type 1 Diabetes

Not Applicable

• Conditions: Type 1 Diabetes
• Interventions: Other: SAFA- Low glycemic index meal; Other: Low fat- Low glycemic index meal; Other: MUFA- High glycemic index meal; Other: Low fat- High glycemic index meal; Other: MUFA- Low glycemic index meal; Other: SAFA- High glycemic index meal

• Registration Number: NCT02330939
• Lead Sponsor: Federico II University

Brief Summary

The purpose of this study is to determine whether dietary fats may affect postprandial glycemic response differently according to their quality, and these effects may differ whether they are assumed in the context of meals with high or low glycemic index in patients with type 1 diabetes. This interaction between quality of fat and glycemic index of carbohydrates may have clinical implication for the calculation of prandial insulin dose in these patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-06
• Primary Completion: 2014-12
• Status Verified: 2015-01
• Study First Submitted: 2015-01-01
• Study First Submitted QC: 2015-01-02
• Last Update Submitted: 2015-01-02
• Study First Posted: 2015-01-05
• Last Update Posted: 2015-01-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

-Type 1 diabetes treated by insulin pump

Exclusion Criteria

• Pregnancy
• Celiac disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
SAFA- Low glycemic index	SAFA- Low glycemic index meal	Participants consumed a meal with low glycemic index and rich in SAFA
Low fat- Low glycemic index	Low fat- Low glycemic index meal	Participants consumed a meal with low glycemic index and poor in fat
MUFA- High glycemic index	MUFA- High glycemic index meal	Participants consumed a meal with high glycemic index and rich in MUFA
Low fat- High glycemic index	Low fat- High glycemic index meal	Participants consumed a meal with high glycemic index and low in fat
MUFA- Low glycemic index	MUFA- Low glycemic index meal	Participants consumed a meal with low glycemic index and rich in MUFA
SAFA- High glycemic index	SAFA- High glycemic index meal	Participants consumed a meal with high glycemic index and rich in SAFA

Primary Outcome Measures

Name	Time	Method
postprandial incremental glucose AUC	6 hours

Trial Locations

Locations (1)

Department of Clinical Medicine and Surgery; 🇮🇹 Naples, Italy