The effect of dietary fats on appetite and metabolism
- Conditions
- OverweightObesityDiet and Nutrition - Other diet and nutrition disordersDiet and Nutrition - Obesity
- Registration Number
- ACTRN12614000466640
- Lead Sponsor
- Dr Maxine Bonham
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 13
Male aged 18-40 years old
BMI 27kg/m2 - 35kg/m2 if you are Caucasian; or BMI 25kg/m2 to 30kg/m2 if you are Asian/Indian
Waist Circumference more than 102 cm if you are Caucasian, or more than 92 cm if you are Asian/Indian
Weight stable (within +/-2kg in the last 6 months)
Non-smoker
Fasting blood glucose levels less than 6.0mmol/L
Fasting triglyceride levels less than 3.0 mmol/L
Fasting cholesterol less than 6.0mmol/
Taking any medications known to alter body composition or metabolism e.g. thyroxin, glucocorticoids
Obesity due to secondary causes relating to genetic or endocrinology related disorders
Lactose intolerant or vegetarian
Diagnosed with, and or on drug therapy for diabetes, high blood pressure, high cholesterol or cardiovascular disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Energy expenditure as assessed by indirect calorimetry[Baseline and at 1,2,3,4,5 and 6 hours after the muffin breakfast];Hunger and Fullness as assessed by visual analogue scale (VAS)[Baseline and at 1,2,3,4,5 and 6 hours after the muffin breakfast];Blood lipid response including triglyceride and cholesterol, as well as insulin and glucose as assessed by blood sampling [Baseline and at 1,2,3,4,5 and 6 hours after the muffin breakfast]
- Secondary Outcome Measures
Name Time Method Appetite hormones including ghrelin, PYY, GLP-1, CCK as assessed by blood sampling[Baseline and at 1,2,3,4,5 and 6 hours after the muffin breakfast]