Comparison of dexmedetomidine, esmolol and combination of both drugs to decrease stress response to intubation.
Not Applicable
Not yet recruiting
- Conditions
- Health Condition 1: - Health Condition 2: Z00-Z99- Factors influencing health status and contact with health services
- Registration Number
- CTRI/2023/01/049139
- Lead Sponsor
- ABVIMS AND DR RML HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American society of Anaesthesiologists(ASA) Physical status I and II Patients
2. Either sex
3. Age: 20 to 50 years
4. Elective surgical procedures
Exclusion Criteria
1. Known sensitivity to any study drug
2. Pregnant females
3. Patient with chronic hypertension and diabetes mellitus
4. Patient with history of cardiac or respiratory disease
5. Patient with anticipated difficult airway
6. Patient with impaired kidney or liver function
7. Patient on Beta blockers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodynamic response to Laryngoscopy and Endotracheal Intubation(HR,SBP,DBP,MAP)Timepoint: Baseline(at arrival in OT) <br/ ><br>1 minute after Laryngoscopy and Endotracheal Intubation <br/ ><br>3 minutes after Laryngoscopy and Endotracheal Intubation <br/ ><br>5 minutes after Laryngoscopy and Endotracheal Intubation
- Secondary Outcome Measures
Name Time Method Biochemical markers of stress response(Serum cortisol and Blood glucose levels)Timepoint: Baseline(at arrival in OT) <br/ ><br>5 minutes after Laryngoscopy and Endotracheal Intubation