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Clinical Trials/NCT06483503
NCT06483503
Active, not recruiting
Not Applicable

A Prospective Cohort Study Evaluating a Novel Colonoscope With a 230-degree Extra-wide Field of View Optics (EFOV)

Pentax Medical1 site in 1 country60 target enrollmentAugust 21, 2024
ConditionsColonic Polyp

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colonic Polyp
Sponsor
Pentax Medical
Enrollment
60
Locations
1
Primary Endpoint
Cecal Intubation Rate
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this observation study is to learn about the feasibility of a new colonoscope which provides the physician an extra-wide field of view during a screening colonoscopy. The main question this study aims to answer is can this new type of colonoscope locate polyps during clinical use in patients.

Patients will undergo a routine colonoscopy for colorectal cancer or polyp surveillance and have one follow-up phone call up to 2 weeks of the colonoscopy.

Registry
clinicaltrials.gov
Start Date
August 21, 2024
End Date
March 30, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Screening for colorectal cancer at the age greater than or equal to 50 years, or evaluation of a positive stool test (i-FOBT) or polyp surveillance.
  • Signed informed consent.

Exclusion Criteria

  • ASA classification ≥
  • Age \<18 years.
  • Known or suspicion of inflammatory bowel disease.
  • Known polyp(s) for polypectomy.
  • High risk for colorectal cancer, history of extensive polyposis, patients with known genetic disease.
  • Prior colorectal surgery.
  • Vulnerable subjects or subjects unable to follow the procedures of the investigation, e.g., due to language problems.
  • Unable or unwilling to undergo bowel cleansing for colonoscopy.
  • Female patients who are pregnant or nursing.
  • Participation in another clinical trial within 30 days prior to the Screening Visit or during this study.

Outcomes

Primary Outcomes

Cecal Intubation Rate

Time Frame: Day 1

The proportion of procedures in which the cecum was reached.

Secondary Outcomes

  • Mean number of polyps per coloscopy and its detection rate(Day 1)
  • Mean number of adenomas and its detection rate(Day 14)
  • Procedure Time(Day 1)
  • Ileum Intubation Rate(Day 1)
  • Mean number of sessile serrate lesions and its detection rate(Day 14)
  • Therapeutic Intervention Success Rate(Day 1)
  • Patient Satisfaction Survey(Day 14)

Study Sites (1)

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