To compare the different laryngoscopes king vision, Mac coy and Macintosh laryngoscopes for tracheal intubation in cases of mucormycosis scheduled for surgery.
- Conditions
- Medical and Surgical, (2) ICD-10 Condition: B488||Other specified mycoses, (3) ICD-10 Condition: B488||Other specified mycoses,
- Registration Number
- CTRI/2021/08/035912
- Lead Sponsor
- UCMSGTBH
- Brief Summary
Mucormycosis ,an emerging angioinvasive fungal infection is associated with high morbidity and mortality. Rhino orbital cerebral mucormycosis (ROCM) is characterised by progressive fungal invasion of the hard palate, paranasal sinuses, orbit, and brain is the commonest variant..
Patients with ROCM , may experience difficult mask ventilation and endotracheal intubation as a result of epiglottitis and supraglottic edema associated with fungal debris.
The armamentarium of the anesthesiologist has a variety of options for difficult intubation . King vision video laryngoscope is one of the latest laryngoscopes as an aid in difficult airway.
However, relative efficacy of this device in comparison with the Macintosh laryngoscope and Mc Coy laryngoscope has not been compared in mucormycosis patients. Therefore, this randomized, prospective study will be planned to compare the effectiveness of Macintosh, McCoy, and King Vision video laryngoscopes to compare the ease of intubation and hemodynamic variables in mucormycosis patients posted for elective surgery .
90 consenting adult patients aged 18-65 years of age of either sex ASA Grade 1 and ASA Grade 2 undergoing elective surgery under general anesthesia with endotracheal intubation will be included in this prospective randomized study protocol.
**The end points of the primary objectives are Mouth opening post induction, Cormack-Lehane grade, time to successful intubation and number of attempts to successful intubation.The secondary objectives will be a heart Rate, Systolic blood pressure and diastolic blood pressure.**
Patients in the A group will be intubated with King ‘s vision video laryngoscope , those belonging to Group B Mc Coy laryngoscope will be used and in Group C Macintosh laryngoscope after induction of anesthesia.
**Sample size will be calculated at 95 % significance level and power of 80%. An alpha error of 0.05 and beta error of 0.2 incorporating three equal size groups of 30 each will be taken. The total number of patients being enrolled will be 90.**
**The second wave of the COVID 19 pandemic has seen a surge in the cases of mucormycosis and hence optimal anesthetic management of patients being scheduled for anaesthesia is vital.**
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 90
All ASA1 and ASA2 patients in the age group of 18- 65 years will be included in this prospective randomized study.
1 Morbid Obesity 2 Pregnancy 3 Bleeding diathesis 4 Severe cardiac or respiratory insufficiency 5 Progressive neurological disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mouth opening after induction, Cormack- Lehane grade, time to successful intubation, number of attempts, any adjuncts used for airway optimization Hemodynamic variables before induction, after induction, 1,2, 3, 5 and 7 minutes after intubation
- Secondary Outcome Measures
Name Time Method Hemodynamic variables like heart rate, systolic blood pressure, diastolic blood pressure, mean blood pressure , ECG and SP02 Pre induction, post induction, 1, 2, 3, 5, 7 minutes of intubation
Trial Locations
- Locations (1)
UCMS/GTBH
🇮🇳East, DELHI, India
UCMS/GTBH🇮🇳East, DELHI, IndiaDr Michell GulabaniPrincipal investigator09873657500michellgulabani@gmail.com