Comparison of post-operative analgesic effect of adding Dexmedetomidine or dexamethasone to lidocaine through local anastasia in forearm surgery
Not Applicable
- Conditions
- Forearm laceration.Injury of nerves at forearm level, Injury of muscle and tendon at forearm levelS54, S56
- Registration Number
- IRCT2016011423473N2
- Lead Sponsor
- Vice Chancellor for research Qazvin University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Patients 20–60 years old; with American Society of Anesthesiologists (ASA) physical status I or II; scheduled for elective forearm surgery.
Exclusion criteria: Presence of underlying diseases such as coagulopathy, peripheral vascular diseases and neuropathy; patient’s avoidance; any history of allergy to local anesthetics; treatment with palliative drugs and those affecting the CNS; addiction; neurologic deficit in respective organ; infection in the site of injection; pregnancy; BMI?20 & BMI>40; the use of drugs which interfere with lidocaine such as beta blockers, cimetidine, phenytoin.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: In 2, 4 and 6 hours after infraclavicular block. Method of measurement: Visual analogue Scales(VAS).;Total analgesic dose administered. Timepoint: During 6 hrs after the infraclavicular block ( With interval 2hrs). Method of measurement: Patient file.
- Secondary Outcome Measures
Name Time Method Onset of sensory and motor block. Timepoint: From the start of anesthetics injection. Method of measurement: Evaluate the patient’s response to needle hitting on surgical site and griping force.;Time of duration of sensory block. Timepoint: The time interval between the time of loss of pain sensation at forearm to reappearance of paresthesia. Method of measurement: Pin-prick test.;Hemodynamic variables of the block. Timepoint: In 5, 10, 15, 20 and 30 minutes after infraclavicular block. Method of measurement: Monitoring system.;Time of duration of motor block. Timepoint: The time interval between the time of loss of pain sensation at forearm to complete recovery of motor function. Method of measurement: Gripping force test.