Clinical observation of Xinqian Ganju Decoction in the treatment of chronic sinusitis and its effect on serum miRNA
- Conditions
- chronic rhinosinusitis
- Registration Number
- ITMCTR2100004577
- Lead Sponsor
- Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) The diagnosis and treatment standard and prescription selection of TCM diseases are referred to in TCM diagnosis and treatment;
(2) The western medicine diagnosis standard is referred to the guide for diagnosis and treatment of chronic sinusitis : the changes of nasal cavity and sinuses, congestion and mucus, etc. have been confirmed by CT and other imaging;
(3) The course of disease was more than 12 weeks;
(4) Patients and their families were informed of the study and signed informed consent.
(1) Pregnant or lactating women;
(2) Chronic sinusitis caused by other bacteria and viruses;
(3) Patients complicated with allergic rhinitis, asthma, bronchitis and other serious respiratory diseases;
(4) Deviation of nasal septum and abnormal nasal structure;
(5) Patients with malignant tumor;
(6) Patients with heart, liver, kidney and other important organ dysfunction;
(7) Mentally abnormal, unable to communicate normally.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptom efficacy index;
- Secondary Outcome Measures
Name Time Method routine blood test;CRP;Nasal mucociliary transport velocity;TNF-alpha;miRNA;IL-2;