Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

Not Applicable

Completed

• Conditions: Kidney Disease

• Registration Number: NCT00018785
• Lead Sponsor: US Department of Veterans Affairs

Brief Summary

Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 1998-10
• Study First Submitted: 2001-07-03
• Study First Submitted QC: 2001-07-04
• Study First Posted: 2001-07-05
• Study Completion: 2003-09
• Status Verified: 2004-12
• Last Update Submitted: 2009-01-20
• Last Update Posted: 2009-01-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Trial Locations

Locations (1)

VAMC Miami; 🇺🇸 Miami, Florida, United States