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Clinical Trials/NCT00018785
NCT00018785CompletedNot Applicable

Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

US Department of Veterans Affairs1 site in 1 countryStarted: October 1, 1998Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.

Study Design

Study Type
Interventional
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Living related donor kidney transplant recipients and the living related donors.

Exclusion Criteria

  • Not provided

Investigators

Sponsor Class
Fed

Study Sites (1)

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Living-Related Donor Bone Marrow... | Clinical Trial