Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia

Not Applicable

Completed

• Conditions: Knee Osteoarthritis; Fibromyalgia
• Interventions: Dietary Supplement: Creatine supplementation; Dietary Supplement: Dextrose supplementation

• Registration Number: NCT00749983
• Lead Sponsor: University of Sao Paulo

Brief Summary

The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-09-09
• Study First Submitted QC: 2008-09-09
• Study First Posted: 2008-09-10
• Study Start: 2009-06
• Primary Completion: 2012-07
• Study Completion: 2012-07
• Status Verified: 2012-10
• Last Update Submitted: 2012-10-01
• Last Update Posted: 2012-10-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Fulfill ACR criteria of knee osteoarthritis
• Fulfill ACR criteria of fibromyalgia

Exclusion Criteria

• Athletes
• Drugs stable for at least three months before entering the study
• No limitations to resistance training

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Creatine supplementation	creatine intake
2	Dextrose supplementation	placebo (dextrose) intake

Primary Outcome Measures

Name	Time	Method
Physical function	12 weeks	Assessed by the timed-stands test

Secondary Outcome Measures

Name	Time	Method
Strength	12 weeks	Assessed by the 1-repetition maximum test
Quality of life	12 weeks	health-related questionaires
Body composition	12 weeks	Assessed by DXA
Renal function	12 weeks	Assessed by 51Cr-EDTA

Trial Locations

Locations (1)

University of Sao Paulo School of Medicine; 🇧🇷 Sao Paulo, Brazil