Effect of calcium chloride injection on the amplitude of motor evoked potential in spine surgery
Not Applicable
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0009367
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
During spine surgery, transcranial motor evoked potentials are measured in adult patients over 18 years of age with normal preoperative muscle strength in both upper and lower extremities.
Exclusion Criteria
Patients who do not consent to the study, do not undergo invasive arterial pressure monitoring during surgery, do not have additional venous catheter insertion during surgery, and whose first arterial blood test during surgery shows an ionized calcium concentration of 1.15 mmol/L or higher.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ratio of the maximum amplitude among the three amplitudes measured at the same site 1, 3, and 5 minutes after the injection of calcium chloride to the initial amplitude based on the amplitude of the transcranial motor evoked potentials measured in the left tibialis anterior muscle before the injection of calcium chloride
- Secondary Outcome Measures
Name Time Method mean arterial blood pressure, pulse rate, peripheral oxygen saturation, bispectral index, body temperature;arterial blood gas analysis;Stimuli used for motor evoked potential and somatosensory evoked potential tests;Amplitude and latency measured in the anterior tibial muscle, abductor hallucis, and abductor pollicis brevis during the motor evoked potential test;Amplitude and latency measured at the frontal pole zero, central zero, and C3'/C4' during the somatosensory evoked potential test