CUMULUS: Comparing Ultrasound Markers of Under recruited Lung in preterm infants on respiratory Support

Not Applicable

Completed

• Conditions: Prematurity; Respiratory distress syndrome; Under recruited lung; Reproductive Health and Childbirth - Complications of newborn; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12621001119886
• Lead Sponsor: The Royal Women's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-08-23
• Study Completion: 2022-11-14
• Last Update Posted: 18 July 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Very preterm infants born <32 weeks gestation and greater than 24 hours of age who require a chest radiograph

Exclusion Criteria

•Congenital lung malformations including congenital diaphragmatic hernia
•Major congenital cardiac defects
•Known pleural effusions or pneumothorax
•Respiratory distress syndrome where decisions about surfactant therapy are being made

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The sensitivity and specificity of an ultrasound derived lung aeration score for radiological diagnosis of under-inflation on chest radiograph as defined by the presence of < 8 posterior ribs visualised at the level of the diaphragm [Lung ultrasound performed immediately before chest radiograph ];The inter and intra observer variability of the lung ultrasound (LUS) derived lung aeration score performed by two investigators at least 1 months apart[Lung ultrasound performed immediately before chest radiograph ]