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Alzheimer's Disease Prevention Trial

Phase 3
Completed
Conditions
Alzheimer Disease
Memory Disorders
Registration Number
NCT00000176
Lead Sponsor
National Institute on Aging (NIA)
Brief Summary

This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.

Detailed Description

PREventing Postmenopausal memory loss and Alzheimer's with Replacement Estrogens (PREPARE) is a double-blind-placebo controlled trial to determine whether estrogen (or estrogen and progesterone) can delay the onset of memory loss or Alzheimer's Disease in elderly women with a family history of the disease.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria
  • Healthy women 65 or older with a family history of memory problems not currently on estrogen.
Exclusion Criteria
  • Significant neurological impairment
  • Current estrogen use
  • History of breast cancer

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (22)

University of Alabama

πŸ‡ΊπŸ‡Έ

Birmingham, Alabama, United States

University of California, Irvine

πŸ‡ΊπŸ‡Έ

Irvine, California, United States

New England Center for Headache

πŸ‡ΊπŸ‡Έ

Stamford, Connecticut, United States

Howard University

πŸ‡ΊπŸ‡Έ

Washington, District of Columbia, United States

Lee Memorial Health System

πŸ‡ΊπŸ‡Έ

Fort Myers, Florida, United States

Mayo Clinic Jacksonville

πŸ‡ΊπŸ‡Έ

Jacksonville, Florida, United States

Wein Center

πŸ‡ΊπŸ‡Έ

Miami Beach, Florida, United States

West Florida Regional Medical Center

πŸ‡ΊπŸ‡Έ

Pensacola, Florida, United States

North Broward Medical Center

πŸ‡ΊπŸ‡Έ

Pompano Beach, Florida, United States

Tallahassee Memorial Health Center

πŸ‡ΊπŸ‡Έ

Tallahassee, Florida, United States

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University of Alabama
πŸ‡ΊπŸ‡ΈBirmingham, Alabama, United States

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