Alzheimer's Disease Prevention Trial
- Conditions
- Alzheimer DiseaseMemory Disorders
- Registration Number
- NCT00000176
- Lead Sponsor
- National Institute on Aging (NIA)
- Brief Summary
This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.
- Detailed Description
PREventing Postmenopausal memory loss and Alzheimer's with Replacement Estrogens (PREPARE) is a double-blind-placebo controlled trial to determine whether estrogen (or estrogen and progesterone) can delay the onset of memory loss or Alzheimer's Disease in elderly women with a family history of the disease.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- Not specified
- Healthy women 65 or older with a family history of memory problems not currently on estrogen.
- Significant neurological impairment
- Current estrogen use
- History of breast cancer
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (22)
University of Alabama
πΊπΈBirmingham, Alabama, United States
University of California, Irvine
πΊπΈIrvine, California, United States
New England Center for Headache
πΊπΈStamford, Connecticut, United States
Howard University
πΊπΈWashington, District of Columbia, United States
Lee Memorial Health System
πΊπΈFort Myers, Florida, United States
Mayo Clinic Jacksonville
πΊπΈJacksonville, Florida, United States
Wein Center
πΊπΈMiami Beach, Florida, United States
West Florida Regional Medical Center
πΊπΈPensacola, Florida, United States
North Broward Medical Center
πΊπΈPompano Beach, Florida, United States
Tallahassee Memorial Health Center
πΊπΈTallahassee, Florida, United States
Scroll for more (12 remaining)University of AlabamaπΊπΈBirmingham, Alabama, United States