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WISECAP Study

Not Applicable
Recruiting
Conditions
Tuberculosis
Registration Number
PACTR202205876377808
Lead Sponsor
Infectious Diseases Institute Makerere University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
164
Inclusion Criteria

1.Newly diagnosed patient of pulmonary MDR-TB and or Rifampicin resistant TB aged 8 years and above.
2.Patients being initiated on the oral MDR-TB treatment
3.Evidence of a personally signed and dated informed consent document (or a legal representative).

Exclusion Criteria

1. Patients with any condition that inhibits the use of the MEMS device e.g. dexterity or debilitating arthritis.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Overall adherence rates among MDR-TB patients on self-administered therapy and on DOT
Secondary Outcome Measures
NameTimeMethod
1.Correlation between serum MDR_TB drug concentrations and adherence data for patients on self-administered therapy and DOT ;Sputum conversion ;MDR-TB outcomes (cure, treatment completion, loss to follow-up or death) in each arm
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