Acute Lung Injury After Aortic Valve Surgery
- Conditions
- Lung Injury
- Interventions
- Procedure: aortic valve surgery with CPB
- Registration Number
- NCT01184313
- Lead Sponsor
- University of Oulu
- Brief Summary
The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.
Study questions:
* Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree?
* Is there any correlation between oxyhaemodynamic parameters and lung injury degree?
* Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers?
* Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- elective aortic valve surgery patient
- written consent
Exclusion Criteria
- none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description aortic valve surgery aortic valve surgery with CPB -
- Primary Outcome Measures
Name Time Method lung injury within the first 3 days after surgery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Oulu University hospital
🇫🇮Oulu, Finland