Acute Lung Injury After Aortic Valve Surgery

• Conditions: Lung Injury

• Registration Number: NCT01184313
• Lead Sponsor: University of Oulu

Brief Summary

The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.

Study questions:

* Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree?

* Is there any correlation between oxyhaemodynamic parameters and lung injury degree?

* Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers?

* Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?

Detailed Description

Not available

Study Timeline

• Status Verified: 2010-08
• Study First Submitted: 2010-08-17
• Study First Submitted QC: 2010-08-17
• Study First Posted: 2010-08-18
• Study Start: 2010-09
• Last Update Submitted: 2010-09-02
• Last Update Posted: 2010-09-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• elective aortic valve surgery patient
• written consent

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
lung injury	within the first 3 days after surgery

Trial Locations

Locations (1)

Oulu University hospital; 🇫🇮 Oulu, Finland