Change in the size of large blood vessel during breathing in and breathing out as a predictor of low blood pressure after spinal anaesthesia in patients undergoing surgery for hip fracture

Not yet recruiting

• Conditions: Fracture of head and neck of femur,

• Registration Number: CTRI/2024/02/062673
• Lead Sponsor: Medica Superspecialty Hospital

Brief Summary

Hypotension causes a significant mortality and morbidity in patients undergoing hip fracture surgery under spinal anaesthesia. 108 patients will be enrolled meeting the inclusion criteria

will be studied. IVC collapsibility index will be calculated preoperatively for each patient and standard spinal anaesthesia will be administered. Blood pressure will be recorded at regular

intervals and episodes of hypotension will be recorded. At the end of the study, correlation between IVC collapsibility index and episodes of hypotension if any will be  identified.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-03
• Last Update Posted: 2024-09-02

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

• 1.American Society of Anaesthesiologists (ASA) physical status I – III.
• 2.Scheduled to undergo hip surgery under spinal anaesthesia.

Exclusion Criteria

1.Patient refusal 2.Absolute or relative contraindication to spinal anaesthesia a)Coagulopathy b)Local site infection c)Symptoms or signs of raised intracranial pressure d)Known allergy to local anaesthetics e)Severe Aortic stenosis or mitral stenosis (Fixed cardiac output state) f)Shock g)Sepsis 3.Failure to perform spinal anaesthesia or inadequate block requiring conversion to general anaesthesia 4.BMI > 30kg/m2 5.Difficulty in identifying intrahepatic IVC.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Episodes of hypotension	Every 3 minutes for the first 15min, at 30 min and every 30 min till the end of the procedure, once in the recovery room and once at 24 hrs after surgery

Secondary Outcome Measures

Name	Time	Method
Episodes of bradycardia, nausea and vomiting, allergic reaction, dizziness, chest discomfort or shivering.	Every 3 minutes for the first 15min, at 30 min and every 30 min till the end of the procedure, once in the recovery room and once at 24 hrs after surgery

Trial Locations

Locations (1)

Medica Superspecialty Hospital; 🇮🇳 Kolkata, WEST BENGAL, India

Medica Superspecialty Hospital

🇮🇳Kolkata, WEST BENGAL, India

Dr Jaya Choudhary

Principal investigator

8017517100

jayachoudhry11@gmail.com