Upper Airway Function and Cardiorespiratory Performance in Impair Trunk Motor Control Multiple Sclerosis Patients.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Universidad de Granada
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Phonation function
- Last Updated
- 6 years ago
Overview
Brief Summary
Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. Different areas are affected, including upper airway function, trunk motor control and cardiorespiratory performance. The aim of this study was to determinate the relevance of trunk motor control in upper airway function and cardiorespiratory performance in patients with multiple sclerosis.
Investigators
Marie Carmen Valenza
assistant professor
Universidad de Granada
Eligibility Criteria
Inclusion Criteria
- •Have a diagnosis of MS in any of its forms according to McDonald criteria
- •Were aged higher than 18 years
- •No pathology in the uppers extremities
- •Capacity to understand and response the questionnaires
- •Ability to provide informed consent.
Exclusion Criteria
- •Cancer diagnoses, cognitive or psychiatric disorders, severe musculoskeletal disorders, severe orthopaedic problems, organ failure, incapacity to cooperate
- •Inability to provide informed consent.
Outcomes
Primary Outcomes
Phonation function
Time Frame: baseline
The phonatory function and it´s repercussion on daily life was evaluated by the Voice handicap index (VHI-30),
Swallowing function
Time Frame: baseline
To evaluate swallowing function we used two questionnaires: the Eating Assessment Tool-10 (EAT-10). The values range from 0 to 4 being higher values worse swallowing function.
Ventilation function
Time Frame: baseline
Ventilation capacity was measured with spirometry and peak flow using Spirobank II (MIR, Italy).
The exercise capacity focussed on lower limbs
Time Frame: baseline
The Five-Times-Sit-to-Stand test (5STS)
The exercise capacity focussed on upper limbs
Time Frame: baseline
The exercise capacity focussed on upper limbs was measured by the unsupported upper-limb exercise test (UULEX)
The anaerobic threshold
Time Frame: baseline
Incremental sit-to-stand test (ISTS)
Trunk motor control
Time Frame: baseline
The impairment of trunk motor control was measured with the Modified Trunk Impairment Scale (mTIS). The values range to 0 from 16 being higher values, better trunk motor control.
Secondary Outcomes
- The impact of the multiple sclerosis disease(baseline)
- Psychological status(baseline)
- The degree of neurological functioning(baseline)