Can a dental care intervention reduce the risk of death of patients treated in intensive care units? A clinical randomized study

Not Applicable

• Conditions: Death attributable to nosocomial lower respiratory-tract infections among adults and elderly patients admitted to intensive care units (ICUs) and to evaluate if dental treatment reduces the occurrence of major cardiovascular events after discharge from the ICU in a subgroup of patients with a high cardiovascular risk. Respiratory Infections; Critical Care; Pneumonia Associated with Mechanical Ventilation; Major Cardiovascular events.; C01.539.739; E02.760.190; C01.539.248.500

• Registration Number: RBR-4jmz36
• Lead Sponsor: Departamento de Medicina Social da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

The intention to treat study population will consist of any patient with ages between 18 to 100 years old admitted for ICU admission during the study period. Subsequently, in the data analysis, those who remain hospitalized for at least 72 hours and have received at least two dental treatment sessions will be considered a per protocol subpopulation.

Exclusion Criteria

Patients who cross the washout period, ie remain in the ICU after the interval of 1 month between the alternation of intervention to control conglomerates and vice-versa, will be excluded from the study. This exclusion will only be from the database for analysis. This does not imply the interruption of dental care if the patient needs it.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of the overall risk of global death and death attributable to nosocomial infections of the lower respiratory tract between adult and elderly patients admitted to ICUs. The relative risk of overall death and attributable to nosocomial infections of the lower respiratory tract between adult and elderly patients admitted to ICUs will be calculated based on the study allocation, whether in the control group or in the experimental group. Patients will be followed up and the outcome evaluated at the time of ICU patient exit by calculation of APACHE II score.<br>