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A Trial to Assess the Antipsychotic Efficacy of ITI-007

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
Registration Number
NCT02282761
Lead Sponsor
Intra-Cellular Therapies, Inc.
Brief Summary

The study will be conducted as a randomized, double-blind, parallel-group, placebo-controlled, multi-center study in patients diagnosed with schizophrenia having an acute exacerbation of psychosis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
450
Inclusion Criteria
  • male or female subjects of any race, ages 18-60 inclusive, with a clinical diagnosis of schizophrenia
  • experiencing an acute exacerbation of psychosis
Exclusion Criteria
  • any subject unable to provide informed consent
  • any female subject who is pregnant or breast-feeding
  • any subject judged to be medically inappropriate for study participation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
60 mg ITI-007ITI-00760 mg ITI-007 administered orally as formulated capsules once daily for 28 days
40 mg ITI-007ITI-00740 mg ITI-007 administered orally as formulated capsules once daily for 28 days
PlaceboPlaceboPlacebo administered orally as formulated capsules once daily for 28 days
Primary Outcome Measures
NameTimeMethod
Positive and Negative Syndrome Scale Total Score28 days
Secondary Outcome Measures
NameTimeMethod
Positive and Negative Syndrome Scale Subscales28 days

Trial Locations

Locations (1)

Clinical Site

🇺🇸

Long Beach, California, United States

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