Fluticasone Propionate-salmeterol Combination Adherence in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Completed

• Conditions: Pulmonary Disease, Chronic Obstructive
• Interventions: Drug: fluticasone propionate/salmeterol xinafoate combination

• Registration Number: NCT01381471
• Lead Sponsor: GlaxoSmithKline

Brief Summary

The specific aim of this study is to describe 1 year Advair dispensing rates for patients with COPD, and to measure the association between Advair adherence and healthcare utilization (e.g. emergency room visits and inpatient admissions, etc.). To compare the risk of a COPD exacerbation (moderate or severe) during a 3-month follow-up period between patients thqat are adherent versus those that are not.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-08
• Primary Completion: 2010-05
• Study Completion: 2010-05
• Study First Submitted: 2011-06-23
• Study First Submitted QC: 2011-06-24
• Study First Posted: 2011-06-27
• Status Verified: 2012-02
• Results First Submitted: 2012-02-02
• Results First Submitted QC: 2012-02-02
• Results First Posted: 2012-03-07
• Last Update Submitted: 2012-03-15
• Last Update Posted: 2012-03-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11060

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COPD	fluticasone propionate/salmeterol xinafoate combination	Patients with a diagnosis code of COPD

Primary Outcome Measures

Name	Time	Method
Mean Number of Pharmacy Claims by Participants During the Post-Index Period	One Year	The mean number of pharmacy claims incurred by participants during the one-year post-index period was measured.
Mean Number of Healthcare Encounters Incurred by Participants During the Post-Index Period	One Year	The mean number of outpatient office visits, inpatient visits, and emergency department visits incurred by participants during the one-year post-index period was measured.