To study the effect of combination of dexamethasone and ropivacaine given in serratus anterior plane with the help of ultrasound in breast cancer surgery.
Phase 3
Completed
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified siteHealth Condition 2: null- Patient having breast cancer will be the participant in this trial
- Registration Number
- CTRI/2018/09/015650
- Lead Sponsor
- All India Institute of Medical Sciences AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
American society of anesthesiologistâ??s (ASA) physical status (PS) I and II
Weight 30-80 kg
Exclusion Criteria
1.Refusal of the patients to give informed consent
2.Preexisting coagulation disorders
3.Morbid obesity
4.Local infection at the site of the block
5.Allergy to the drug under study
6.Patient with severe chest wall deformity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first rescue analgesia in the postoperative period in woman undergoing modified radical mastectomy under general anaesthesia with SAP Block with placebo and SAP block with dexamethasone.Timepoint: Within first 24 hours post MRM
- Secondary Outcome Measures
Name Time Method Total fentanyl consumption during intraoperative period among the two groups. <br/ ><br>Total doses of diclofenac(75 mg) consumed in the post operative period in 24 hours. <br/ ><br>Total tramadol consumption(mg) in the post operative period in 24 hours. <br/ ><br>Occurrence of nausea and vomiting in post-operative period. <br/ ><br>Timepoint: Intraoperative and first 24 hours postoperative.