The Role of Carotis Flow Time in Prediction of Hypotension After Anesthesia Induction in Elderly Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Flow Time
- Sponsor
- Cukurova University
- Enrollment
- 138
- Locations
- 1
- Primary Endpoint
- anesthesia induction related hypotension
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between pre-anesthesia FTc and the magnitude of the maximum decrease in systolic blood pressure from the pre-anaesthetic value.
Detailed Description
The FTc value of the patients to be included in the study will be measured by ultrasonography 10 minutes before the induction of anesthesia.After the measurement, the patients will be monitored with 3-lead electrocardiography, pulse oximetry and noninvasive blood pressure in the operating room. Before induction of general anesthesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), oxygen saturation and heart rate will measured for 3 minutes at 1-minute intervals. Induction of anesthesia with 1-2 mg/kg propofol, muscle relaxation will be achieved with 0.6 mg/kg intravenous rocuronium. During mask ventilation, 1-2% concentration of sevoflurane and 50-50% oxygen-nitrous oxide will be used. After the anesthesia induction, SBP, DBP, MAP, oxygen saturation and heart rate will be measured for 3 minutes at 1-minute intervals. Hypotension; defined as a 30% reduction in SBP or a 20% reduction in MAP, or an absolute SBP below 90 mm Hg and MAP below 65 mm Hg within 3 minutes of induction of general anesthesia.Intravenous (iv) noradrenaline and/or iv crystalloid will be used in the treatment of hypotension.
Investigators
mediha turktan
associate professor
Cukurova University
Eligibility Criteria
Inclusion Criteria
- •\>65 years old
- •undergoing elective surgery under general anesthesia
Exclusion Criteria
- •Mean arterial pressure \< 70 mmHg
- •Systolic blood pressure \> 180 mmHg
- •Diastolic blood pressure \> 110 mmHg
- •\< 65 years old
- •Carotid artery stenosis \> 50%
- •Left ventricle ejection fraction \< 40%
- •Severe peripheral vascular disease
- •Implanted pacemacer
- •Autonomic nervous system disorders
- •Heart valve disease
Outcomes
Primary Outcomes
anesthesia induction related hypotension
Time Frame: at 1 minute after anesthesia induction, at 2 minutes after anesthesia induction, at 3 minutes anesthesia induction
Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP) were measured 1 minute before anesthesia induction and after anesthesia induction (at 1 minute intervals for 3 minutes). Hypotension was defined as 30% decrease in SBP or a 20% decrease in MAP or absolute SBP less than 90 mm Hg, and MAP below 65 mm Hg within 3 minutes of induction of general anaesthesia.