Carotid Artery Corrected Flow Time Measured by Ultrasonography as a Predictor of Hypotension After Induction of General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- corrected flow time (FTc) in carotid artery
研究概览
简要总结
Hypotension often happens immediately after anesthetic induction. Particularly in 5-10 minutes after anesthetic induction it is reported to happen more frequently. Patients may have preexisting hypovolemia resulting from dehydration and impaired compensatory responses, which increase the risk. However, it is still challenging to assess intravascular volume status in spontaneously breathing patients before anesthetic induction. Recently, the measurement of corrected flow time in carotid artery was introduced as quite useful, simple and noninvasive for the evaluation of circulating blood volume. The aim of this study is to evaluate whether corrected carotid artery flow time as determined by ultrasonography in spontaneously breathing patients before general anesthesia can predict hypotension after induction.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients (19-80 years of age) who were scheduled to undergo elective surgery under general anesthesia
排除标准
- •mean blood pressure < 70 mmHg before induction of general anesthesia
- •Patients who have currently taken angiotensin-converting enzyme inhibitor
- •Patients who have currently taken angiotensin receptor blocker
- •the presence of carotid artery stenosis > 50%
- •cardiac rhythm other than sinus
- •unstable angina
- •a left ventricular ejection fraction of < 40%
- •severe vascular disease
- •implanted pacemaker/cardioverter
- •autonomic nervous system disorders
- •anticipated difficult airway
- •pregnancy
结局指标
主要结局
corrected flow time (FTc) in carotid artery
时间窗: 10 minutes before induction of general anesthesia.
the area under the receiver operating characteristics curve of corrected flow time in carotid artery measured by ultrasonography to predict hypotension after anesthetic induction
次要结局
未报告次要终点