Preoperative Lugol’s solution in Graves’ disease and toxic nodular goiter
Phase 1
- Conditions
- HyperthyroidismMedDRA version: 20.0Level: PTClassification code: 10020850Term: Hyperthyroidism Class: 100000004860Therapeutic area: Diseases [C] - Hormonal diseases [C19]
- Registration Number
- CTIS2024-517110-15-00
- Lead Sponsor
- Karolinska University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
Pilot study: Hyperthyroidism due to toxic nodular goiter. Age 18-75 years. Main study: Hyperthyroidism due to toxic nodular goiter and Grave's disease accepted for thyroidectomy. Age 18-75 years.
Exclusion Criteria
Unstable coronary artery disease Previous thyroid surgery Congestive heart failure Renal failure Liver failure Current infection Ongoing treatment with glucocorticoids Ongoing treatment with anticoagulants Thyroid associated ophtalmopathy CAS >2 Diabetes mellitus type1 Active cancer Severe psychiatric illness Amiodarone treatment Pregnancy Breast feeding Women with childbearing potential not using contraception Unability to comprehend the meaning of the study Iodine hypersensitivity
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method