The effects of improving oxygen concentration in the reduction of dialysis induced myocardial stunning – A pilot study - Oxygenation and myocardial stunning

Phase 1

• Conditions: Chronic renal failure patients who are receiving haemodialysis treatment; MedDRA version: 9.1 Level: LLT Classification code 10066623 Term: Chronic haemodialysis

• Registration Number: EUCTR2007-004012-31-GB
• Lead Sponsor: Derby Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-04-16
• Study Completion: 2012-08-15
• Last Update Posted: 25 November 2019

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

1.Patients on HD treatment at least 3times/week.
2.Willing to provide consent.
3.Male and female, age>18 years old.

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1.Dialysis for <4 months
2.Unable to obtain echocardiographic data of sufficient quality to allow analysis
3.Cardiac transplant recipients
4.NYHA IV heart failure
5.Chronic obstructive airway disease, other chronic/acute lung condition exacerbating hypoxia and/or unable to tolerate O2 therapy.
6.Patients on long term oxygen therapy (LTOT).
7. Pregnant women or female subjects in childbearing age.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified