Effect of botulinum toxin injection versus placebo injection in fat pad around the heart on the incidence of intra-hospital atrial fibrillation after open-heart surgery: a double-blind randomized clinical trial
Phase 2
Recruiting
- Conditions
- Atrial fibrillation.Atrial fibrillation and flutter
- Registration Number
- IRCT20120215009014N350
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age of 18 to 80 years,
Indication of open-heart surgery
Exclusion Criteria
History of previous hear surgery,
Unstable angina or heart failure,
Chronic atrial fibrillation,
Aortic or mitral valvular disease,
Liver or renal or thyroid disorder,
Taking anti-arrhythmic medications
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intra-hospital atrial fibrillation after open-heart surgery. Timepoint: Daily for 7 to 10 days. Method of measurement: With monitoring machine.;Left ventricular ejection fraction. Timepoint: Before open-heart surgery and one month after that. Method of measurement: Using echocardiography.
- Secondary Outcome Measures
Name Time Method