Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods
- Conditions
- Drug Resistant Bacterial Infection
- Interventions
- Diagnostic Test: ARES PCR
- Registration Number
- NCT06308692
- Lead Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
- Brief Summary
Experimental study without drug and device, on pseudo-anonymized samples archived at the Tropica Biobank.
The objective is to evaluate the performance for the identification of microorganisms in blood samples and rectal swabs of real time PCR assays for the targets: KPC, VIM, IMP, NDM, Acinetobacter OXA, Oxa48, MCR.
The evaluations will be carried out taking into consideration the data obtained from the diagnostic routine at the DITM.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Biological samples ARES PCR Residual anonymized samples stored at -80°C at the Tropica Biobank of the DITM and for which diagnostic analysis for germ infection has previously been carried out at the DITM by blood culture and MDR surveillance in routine diagnostic rectal swab will be used.
- Primary Outcome Measures
Name Time Method PCR results Baseline Results (positive/negative and microorganism identification) obtained by real time PCR.
- Secondary Outcome Measures
Name Time Method Gene mutations Baseline Results (resistant/susceptible) obtained by real time PCR in the identification of gene mutations that convey resistance to antibiotics.
Trial Locations
- Locations (1)
IRCCS Sacro Cuore Don Calabria hospital
🇮🇹Negrar, Verona, Italy