Hypotensive effects of Umezu polyphenols among community-dwelling hypertensive patients not requiring medicatio
- Conditions
- Hypertension
- Registration Number
- JPRN-UMIN000029394
- Lead Sponsor
- Wakayama Medical University
- Brief Summary
Some potential effects of Umezu polyphenols to prevent blood pressure elevation and to improve self-perceived physical health were observed. After withdrawal of Umezu polyphenols, this self-perceived physical health gradually returned to the initial level within one year.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
(1) People who eat two or more Umeboshi (pickled plums) per day regularly, (2) people with ingestion difficulty, (3) people with history of serious chronic conditions including cerebrovascular disease, ischemic heart disease and cancer (malignant tumor), (4) people under medication for hypertension, (5) people who are pregnant or within 1 year after delivery, (6) people having night-shift work with night duty, (7) people who cannot participate in follow-up blood pressure measurements, and (8) people whose participation is judged to be inappropriate due to any other reason by the responsible physician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decrease of systolic blood pressure and diastolic blood pressure after 12 weeks of intake of Umezu polyphenols in (1) blood pressure at home, and (2) blood pressure at the examination site
- Secondary Outcome Measures
Name Time Method Findings from blood tests (hematology and biochemistry) Anthropometric factors Self-perceived physical and mental health status evaluated with SF-8 Self-perceived Symptoms Changes in data of annual health checkups