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临床试验/NCT07177989
NCT07177989招募中不适用

Combined Effects of Alternate Nostril Breathing and Aerobic Interval Training on Blood Pressure and Heart Rate Products in Patients With Hypertension

Foundation University Islamabad2 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2025年1月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
36
试验地点
2
主要终点
heart rate

研究概览

简要总结

Hypertension (HTN) is the foremost preventable risk factor for cardiovascular disease (CVD) and all-cause mortality, contributing to over 7 million deaths annually within the nearly 17 million attributed to CVD. Effective management through lifestyle modifications, including aerobic exercises specifically interval training presents a promising avenue for blood pressure regulation by promoting vasodilation and regulating the autonomic nervous system. Likewise, alternate nostril breathing has demonstrated efficacy in lowering blood pressure by optimizing oxygenation and improving endothelial function but their combined effect on BP measures is yet to be determined. Hence this study aims to determine the combined effects of aerobic interval training with and without alternate nostril breathing on blood pressure, rate pressure product and quality of life in patients with hypertension.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
25 Years 至 50 Years(Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Adults aged 25- 50 years -males and females
  • •Patients diagnosed with stage 1 hypertension 130 - 139 / 80 - 89 mmHg and stage 2 hypertension, BP level ≥140/90 mmHg. according to AHA/ACC 2017 Guidelines-Individuals who are able to understand and follow the instructions for exercise

排除标准

  • •Diagnosed with any current infections
  • •subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program
  • •Active Smokers
  • •Those with any contraindication to exercise testing or training.
  • •Pregnant females

研究组 & 干预措施

Interventional group (Group B)

Experimental

Patients in this group will perform alternative nostril breathing along with aerobic interval training.

A protocol of total 5 weeks. Three sessions per week on alternate days will be done under the supervision of physiotherapist.

All outcome measurements would be performed first at baseline and terminal after the 5 weeks intervention period

干预措施: Experimental Group (Other)

Interventional group (Group A)

Active Comparator

Patients in tis group will perform aerobic interval training. A protocol of total 5 weeks. Three sessions per week on alternate days will be done under the supervision of physiotherapist.

All outcome measurements would be performed first at baseline and terminal after the 5 weeks intervention period

干预措施: interventional group A (Other)

结局指标

主要结局

heart rate

时间窗: 05 weeks

heart rate will be measured by pulse oximeter

blood pressure

时间窗: 05 weeks

it will be measured by pulse oximeter

Rate pressure product

时间窗: 05 weeks

it will be evaluated by formula : systolic blood pressure x heart rate resting by using sphygmomanometer

heart rate

时间窗: 05 weeks

heart rate will be measured by pulse oximeter

blood pressure

时间窗: 05 weeks

it will be measured by pulse oximeter

Rate pressure product

时间窗: 05 weeks

it will be evaluated by formula : systolic blood pressure x heart rate resting by using sphygmomanometer

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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